Anabolic Effects, Direct and Indirect


Almost everyone knows that anabolic effects steroids are harmful to health, and professional athletes carry out anti-doping tests.

anabolic effectsIf an athlete caught doping at the reception, then impose sanctions. This situation is legitimized by the World Anti-Doping Agency, which has a list of prohibited steroids.

Every year this list is updated: stanozolol, methandrostenolone, retabolil ….

However, for amateurs and semi-professionals the rules are not as strict, jay cutler and many bodybuilders allow themselves from time to time to use illicit drugs. And in this lies the great danger to human health. Some believe that only the regular intake of steroids is anabolic steroids guide harmful to the body. In addition, it is believed that the periodic doping is useful for the body: drugs stimulate the metabolism of proteins, thereby increasing the weight, accelerated regeneration.

But this is a misconception. No matter how often you take anabolic steroids, in any case they have an irreparable harm to the body. Any chemicals should be prescribed by a doctor. To receive each drug and anabolic steroids also apply to those, we need some evidence. Remember that anabolics – is hormonal drugs, while taking which develop certain complications.

One of the major complications of steroids is a disruption of the endocrine system. The main component of anabolic – androgen is the male sex hormone. If a man takes the drug, he has problems begin with the men’s sphere: decreased libido, impotence occurs, you may have prostate cancer. Women are also the result is disappointing – begin to develop male sexual characteristics: grow hair coarsens his voice, and the ability to conceive a healthy child becomes a general question.

Steroids have a complex anabolic effectson the body. In none of the system, which would not suffer when taking anabolic steroids. This digestive system (nausea, vomiting, diarrhea, cirrhosis of the liver), and cardio – vascular (hypertension development, tachycardia), nervous (mood swings, aggression, and then a sharp apathy). In addition, the muscular system, the development of which the athletes involved in bodybuilding, and take these products, also suffering. Muscle mass is growing so fast that do not stand up and ligaments are torn. And another thing, what you need to remember, taking a drug, it is possible to stimulate the formation of tumors in the body.

So do not think that a single use of steroids, for example, before the competition bodybuilding, will not have an adverse anabolic effects on the body.

In addition, the “pitching” very often want to get a quick result from taking anabolic, but the anabolic effects develops gradually, so athletes are beginning to take large doses to accelerate the process.

The first mention of steroids in sports refers to 1866, when there were the first victims. Over time, the number of victims began to grow, and among them were famous athletes, such as Nikolai Shilo, who at the age of 26 years died of a crack due to a weakened immune system after taking steroids. “Mr. America” ​​Denis Nyaman died of leukemia, and the “Mr. Olympia” from the famous Mohammed Benaziza thrombosis. Increased mortality of athletes under the age of 18 years. So it is necessary to think carefully before you even once to take a drug.

Although testosterone has been isolated from the body and synthesized in vitro, and has been used actively for laboratory studies, but still among the experts there is no consensus about how steroids affect muscle mass.

Currently, under the action of anabolic steroids realize direct involvement of cellular androgen receptors and increased protein synthesis. So, if we can increase our level of androgens by administration of testosterone or a similar anabolic steroids, we can very stronger workout greatly increase the protein content in muscle. This is obviously the main reason for muscle growth while using steroids. Once increased levels of hormones in the body, immediately activated androgen receptors, and of course, the level of protein synthesis.

Other indirect mechanisms of action of hormones may possibly affect the growth of muscle mass in the process of bypassing the direct anabolic effects of androgens on protein synthesis. Under the indirect mechanism of action of hormones to understand the effect of androgens on other hormones, or even the release of hormones, acting locally, or growth promoters inside cells (perhaps they serve as intermediaries for other membrane receptors related cells).

It should be remembered that muscle growth is dependent not only on the protein synthesis, but also on other factors such as the delivery of nutrients to the tissue and protein breakdown. In order to get the fullest possible picture of this process, it is necessary to consider the interaction of androgen in combination with all the other factors. Recent studies suggest that testosterone does not lead the bodybuilding truth book to increased tissue additions to amino acids. This may explain the total combined effect of insulin – a hormone that significantly affect the nutrient delivery to muscle cells. This feature noted by many athletes in recent years. As for the breakdown of proteins, it seems to us, the second a long way possible anabolic effects of androgens on muscle mass.

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