Essentiale forte contains essential (essential) phospholipids, hence the name of the drug.
What are the phospholipids? This polar molecule, one end thereof has an affinity for the fats, it has no charge and is represented generally chain carbon atoms, the other – attracts water, and a residue of phosphoric acid, it is negatively charged. Due to this structure, the phospholipids form a bilayer-like cake, “dough” had two sides represented the polar heads, and “filling” inside – carbon tails. Evolutionary bilayers – the first form of organized matter, the prototype of a primitive cell membrane.
Thus, phospholipids – the main component of cell membranes. They necessarily include phosphoric acid and some organic compound based on a carbon chain. These compounds can be different, most often organic alcohols:
Choline is 75% of the phospholipid membranes and mitochondria – 92%. It is a part of phosphatidylcholine Essentiale Forte. Another of his name – lecithin.
Therefore, the drug Essentiale forte is used to repair damaged any agent of liver cell membranes (hepatitis of any origin, including pregnant women, cirrhosis, non-alcoholic and alcoholic liver disease, diabetes and other nepechenochnaya pathology of liver damage) and to improve bile and cholesterol metabolism.
Essentiale forte is necessary and healthy people, with non-diet, fatty meals and alcohol.
All preparations of phospholipids are fundamentally different according to three criteria:
To answer this question, we must remember that the treatment of diseases may be causative (elimination of the reason), pathogenic (influence on the mechanism of the disease) and symptomatic (elimination or relief of symptoms).
Since the main causes of IBS – diet and stress disorders, there is no way to help phospholipids. On symptoms – bloating, diarrhea and constipation – phospholipids also affect very remotely and indirectly. The mechanism of development of the symptoms of IBS – a violation of motility and secretion, goiter – phospholipids also not involved. So, welcome Essentiale in IBS is useless? No. But do not expect a rapid and complete recovery of the drug. Phospholipids improve the condition of the liver and normalize bile secretion, which leads to the disappearance of intoxication, normalization of stool and improving portability of fatty foods. Essentiale – drug treatment and preventive, pathogenetic series. It is necessary to take a long time, for 2-3 courses per year, to maintain and improve the health of the liver, and not as a “first aid” with discomfort in the digestive tract!
There are a number of Russian and foreign research, marking the effect of the drug, manifested in:
Pharmacological action: the active drug substance – essential phospholipids – are the main components of cell membranes and structures. The phospholipids that make up the drug Essentiale forte N, correspond in their chemical structure of cellular phospholipids, but superior to cellular phospholipids in activity due to a high content of polyunsaturated fatty acids.
Insertion of these high-energy compounds in the damaged areas of the cell membrane restores the integrity of liver cells and promote their regeneration; increased activity of the fixed on the membranes of enzymes, improves metabolism.
The phospholipids that make up the drug Essentsialeforte H tolerate neutral fats and cholesterol oxidation in places, it transforms into forms that facilitate the process of metabolism. Thus, it is a normalizing effect on the metabolism of lipids and proteins; for the restoration and preservation of the cellular structure of the liver, which reduces the exposure to toxic substances and remove them from the body.
Essentiale forte N – is the trade name of the drug to maintain liver health, distributed in Europe by Aventis Pharma. In Russia, the most common Essentiale company A. Nattermann GmbH End these things. (Germany) and Aventis Pharma (Russia).
Although in some regions is considered as a medicinal drug, in fact it contains a set of natural vitamins and phospholipids. In addition, in many countries, including the United States, Essentiale Forte N is sold without a prescription.
The product contains vitamins B complex, vitamin E and phospholipids, linoleic, linolenic and oleic acids. Essentiale Forte N is widely used in Europe for the treatment of liver dysfunction caused by chronic infections, allergies, drug toxicity or other diseases.
Essentiale Forte N is used in bodybuilding athletes who take steroids, because of its ability to reduce liver damage caused by the intake of anabolic / androgenic steroids (especially with the 17-alpha alkali compounds).
The main mechanism of action with Essentiale forte N – supply of antioxidants in the body and the elements necessary for the restoration of damaged cells.
The product contains mainly polyunsaturated phospholipids (mostly phosphatidyl choline), and vitamin B complex and E. Phosphatidylcholine – a cell membrane, a key component of the formula Essentiale forte N. This phospholipid is important for maintaining cell integrity, its flexibility and strength. Phosphatidylcholine is considered an important agent for the liver, providing support for the normal metabolism of fat and the overall health of the liver. Moreover, phosphatidylcholine is a major antioxidant providing healthy liver and pancreas. Vitamins included in Essentiale forte N formula, increase the antioxidant and regenerative properties of the drug.
Essentiale Forte N – is the first product, a softening hepatotoxic effects of anabolic steroids when used in clinical trials. In these tests we examined the effect of high doses of steroids (with or without the application of Essentiale forte H) compared with the control group (not using steroids). To determine the relative levels of hepatic stress tests used all liver enzymes.
As expected, the group receiving steroids, there was a significant increase in liver enzymes. In the group receiving steroids together with Essentiale forte N, the level of liver enzymes was also increased, however, it was close to the control and remained in the normal range. The researchers concluded: “Communication AAS abuse severity with increasing levels of liver enzymes suggests a connection between AAS abuse and damage to liver cells. However, when used in conjunction with AAS Essentiale Fort H … hepatotoxic effect is weakened. ” Despite the fact that the results of one study can not guarantee complete clarity in the application of hepatotoxicity of anabolic steroids it is highly recommended to use Essentiale Forte N.
Essentiale Fort H distributed in Western and Eastern Europe by Aventis for many years. This compound has been approved for the treatment of hepatic steatosis and other disorders of the liver. European bodybuilders used this drug for many years due to its positive impact on the health of the liver. In 2008, the drug has attracted the attention of athletes in the United States and Canada, when in the journal Clinical Toxicology published a study on the results of its use in individuals who abuse steroids. Since then, the popularity of this natural product among North American consumers has increased significantly.
Essentiale forte N comes in soft gelatin capsules,
containing vitamin B1 (6 mg), vitamin B2 (6 mg), vitamin B6 (6 mg), vitamin B12 (6 mg), vitamin E (6 mg), nicotinic acid ( 15 mg) and phospholipid complex [polyene phosphatidylcholine] (holifosfornoy diglyceride esters of unsaturated fatty acids and linoleic acid, linoleic acid and oleic acid) (300 mg).
It should be noted that in the Russian part of Essentiale somewhat different: essential phospholipids EPL – phosphatidylcholine from soybeans containing 76% (3-sn-phosphatidyl) choline – 300 mg;
Other ingredients: hard fat – 57 mg; soybean oil – 36 mg; hydrogenated castor oil – 1.6 mg; Ethanol (96%) – 8.1 mg; ethyl vanillin – 1.5 mg; 4-methoxyacetophenone – 0.8 mg; α-tocopherol – 0.75 mg
Adverse effects of Essentiale Forte N
Essentiale forte N – natural drug addition without causing significant side effects.
Essentiale forte: instructions for use
is the most common recommended dose for the treatment of liver failure is 2 capsules 3 times a day with meals. Bodybuilders and athletes use a medicine for reducing stress liver after oral administration of steroids are usually at the same doses.Tags: essentiale forte, essentiale forte dosage, essentiale forte n, essentiale forte side effects, essentials forte